Lab Researcher - Genomics
National Jewish Health/*National Jewish Health - Main Campus/Genetics
Full Time (40 hours per week)
Work Hours: 8:00 am - 5:00 pm
Req # 13075
National Jewish Health is currently seeking a Genomics Lab Researcher to join the dynamic laboratory team of the genomics facility. The genomics facility is dedicated to bringing cutting edge genomic technologies to the research and clinical community.
The ideal candidate must be first and foremost - detailed oriented, enthusiastic, and able to work with minimal supervision once trained. Equally, the candidate must be able to multi-task and balance multiple projects, show excellent written and verbal communication skills, and should have an academic background in biology. Knowledge of NGS, Sanger sequencing, LIMS and basic molecular biology techniques is highly desirable.
The ideal candidate is a responsible, dedicated team player, who will perform routine laboratory tests under the direction of the lab manager. In addition, the candidate should:
- Demonstrate the ability to understand oral and written documentation, write lab reports, understand and implement lab procedures, and communicate effectively in a variety of situations
- Show functional knowledge of principles, practices and techniques in DNA/RNA extraction protocols and analyses, Sanger Sequencing, PCR, QC assays - demonstrated by knowledge, understanding and ability to apply concepts, terminology
- Be personable and demonstrate the ability to recognize problems, troubleshoot, and resolve typical laboratory issues; and
- Demonstrate the ability to establish and maintain effective working relationships with internal and external organizations, groups, team members and individuals.
The position is responsible for planning, developing, executing, monitoring and testing high level, technically-demanding genomic sequencing techniques and investigative procedures under the direction of a Principal Investigator or Lab Manager.
- Develops new cellular, molecular, and/or genomic techniques and investigative procedures, including novel scientific procedures, computer/robotic programming techniques, and/or data reporting techniques.
- Monitors quality control of procedures, experiments, general laboratory activities, sample tracking, and/or the use of research animals or human subject samples in the laboratory setting.
- Performs specialized, complex, and technically demanding laboratory functions including, but not limited to robotics, gene expression profiling, genomics, next generation sequencing, epigenomics technologies, CRISPR-Cas9 technology, scRNA-seq, and/or CITE-seq.
- Develops and performs novel NGS assays, including but not limited to new methodology for sample preparation, genomic/epigenomic modification, library build, or sequencing.
- Provides general guidance to laboratory staff, including technicians, support and auxiliary staff. Acts as a leader for laboratory programs and staff in assigned areas.
- Demonstrates enhanced proficiency in data analysis, sample tracking, extraction and sample preparation procedures, programming and analysis systems.
- Prepares statistical tabulations using advanced analysis programs and tools.
- Oversees supply functions, inventory control, equipment use and maintenance, and animal care and ordering, as needed.
- Maintains compliance with all institutional / safety training requirements.
- Maintains laboratory records, supplies, samples in an organized manner (such as a laboratory notebook and sample storage record).
- Acts a liaison to other department personnel, outside investigators, and vendors.
- Designs and performs routine and non-routine tests leading to the successful completion of developed experiments.
- Accountability: Accepts full responsibility for self and contribution as a team member; displays honesty and truthfulness; confronts problems quickly; displays a strong commitment to organizational success and inspires others to commit to goals; demonstrates a commitment to National Jewish Health.
- Laboratory Knowledge: Demonstrates and understands laboratory testing and methodology.
- Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience, and judgement. Sought out by others for advice and solutions.
- Adaptability: Maintains effectiveness in the midst of change in work responsibilities or environment, requirements ambiguity, or stress.
- Problem Solving: Uses issue identification, data relation and comparison, pattern recognition and information gathering to create analyses and make recommendations.
- Informing/Communicating: Conveys ideas, responses, or instructions effectively, appropriately, and persuasively through writing or speech.
- Professional Relationships: Interacts with others in a constructive, positive, and respectful manner, regardless of individual differences. Assists team members or co-workers in achieving personal goals and completing assignments.
- Drive for Excellence: Consistently meets performance expectations, ensures that accurate, objective, and timely measures of quality are made and used.
- Innovation Management: Identifies key trends, opportunities, and organizational capabilities that would bring competitive advantage to the organization. Sees trends before others and integrates concepts in a unique way.
Supervisory or Managerial Responsibility
- Be available to work as scheduled and report to work on time.
- Be willing to accept supervision and work well with others.
- Be well groomed, appropriately for your role and wear ID Badge visibly.
- Be in compliance with all departmental and institutional policies, the Employee Handbook, Code of Conduct and completes NetLearning by due date annually.
- Fosters an inclusive workplace where diversity and individual differences are valued and leveraged to achieve the vision and mission of the institution.
- Adheres to safe working practices and at all times follows all institutional and departmental safety policies and procedures.
- Wears appropriate PPE as outlined by the infection control policies and procedures.
- Demonstrates compliance with all state, federal and all other regulatory agency requirements.
BS /BA Degree in Molecular Biology or related field required. Master’s Degree in a molecular biology field is advantageous.
- 1-2 years of Genomics-based Laboratory Experience required, and at least 2 years experience in a laboratory setting or
- A Master’s Degree and some genomics laboratory experience may be substituted for the required 1-2 years of Genomics-based laboratory work experience.
Special Training, Certification or Licensure
Candidate should have familiarity with multiple advanced, technically demanding genomics approaches, including but not limited to NGS pipelines, single-cell approaches, epigenomics, CRISPR-Cas9 approaches, and/or 3D Genomic protocols.